As the photo sharing service hits 80m users, Twitter cuts ties.
Since launching in October 2010, Instagram has now reached 80m registered users, who have shared four billion pictures between them.
However, Instagram users are now no longer able find their friends using Twitter - the API has been disabled.
Instagram users who attempt to access Find Your Friends to discover contacts are now shown an error message stating "Unable to Find Friends. Twitter no longer allows its users to access this information in Instagram via the Twitter API. We apologize for any inconvenience."
This isn't the first time Twitter has cut ties with a rival service, in June they prevented syncing with LinkedIn and there is speculation that this latest decision has been pushed through due to Facebook's purchase of Instagram.
Twitter spokesperson Carolyn Penner said: “We understand that there’s great value associated with Twitter’s follow graph data, and we can confirm that it is no longer available within Instagram."
Moving away from Instagram and LinkedIn are in line with recent statements from Twitter CEO Dick Costolo, who says he wants a world where instead of companies "building off Twitter", they build into it.
Are the days of social media platforms peacefully coexisting over?